Animal studies show that it may increase testosterone, but only at specific doses too high doses can have a negative impact on long-term health. It may also help combat excess body fat, and help restore muscle tone. Although Bulbine natalensis has been used in Africa for years, only recently has it become popular as a supplement in Western medicine. The anterior pituitary regulates the production of LH and FSH. Afr J Tradit Complement Altern Med. Phytomedicine 2021;81:153416. There was a 21% increase in the various lab values indicating kidney damage. USA:10685-B Hazelhurst Drive #24960, Houston, TX 77043. [1], Luteinizing hormone does not appear to be influenced in female rats. This should not be considered medical advice. The more I research Bulbine Natalensis the better it gets. In addition to its uses in the treatment of various medical conditions, Bulbine natelensis is effective for treating wounds and skin problems. Hand picked related article: If youre going to be getting blood drawn, you might as well check your T levels. It is used in traditional African medicine to treat a variety of ailments - from bug stings to mosquito bites, blisters, cold sores, mouth ulcers, cracked skin, sunburn, cuts and even to speed the healing of bruises. For the best experience on our site, be sure to turn on Javascript in your browser. [4] Its a process that is always happening. Whatever times you decide to take it, be sure to follow that routine for the extent of supplementation. [1] Testicular levels of testosterone followed a similar pattern, and in both blood and testes the best dosage was 50mg/kg followed by 25mg/kg and then 100mg/kg. [5] These aphrodisiac effects, when dosed at 25-50mg/kg bodyweight, are more effective than Viagra at 50mg/kg bodyweight. Also, it boosts levels of testicular cholesterol, which is important for testosterone production. Currently, the histopathological changes that have been noted in rats have not been sufficiently addressed in humans. The study was also privately funded by a company that manufactures and profits from sales of this supplement which has its own potential issues. Specifically, we see an effect on the lipoprotein HDL. The system breaks down when cycles cause mass fluctuations in labs and blood work. Due to its influences on cognition and sexuality, it is currently being investigated for its effects on testosterone. Bulbine natalensis leaf might slow blood clotting. It is said to have anti-inflammatory properties. In conclusion, Bulbine Natalensis Extract is a powerful herbal supplement that offers a wide range of health benefits, from testosterone boosting and muscle growth to anti-inflammatory and antioxidant properties. On the other hand, an increase in internal testosterone production has the opposite effect. OTHER NAME(S): Bulbine latifolia, Ibhucu, Ingcelwane, Rooiwortel. Worryingly, the results suggested astatistically significant increase in the liver enzyme, alkaline phosphatase an important enzyme produced in the liver thathelps break down proteins in the body. In two studies, Bulbine Natalensis significantly increased testosterone and follicle-stimulating hormone levels. ProLensis is just one of the ingredients. This also allows you to customize your dosage to fit your individual needs. 2009;72(3):322-32. If you ever have any questions on the legal status of some rare herb or supplement, you can always head over to the DEAs website and find out. Interactions with Sex Organs and Fertility, Anabolic and androgenic activities of Bulbine natalensis stem in male Wistar rats, A biochemical comparison of the in vivo effects of Bulbine frutescens and Bulbine natalensis on cutaneous wound healing, Effect of aqueous extract of Bulbine natalensis (Baker) stem on the sexual behaviour of male rats, Effect of aqueous extract of Bulbine natalensis Baker stem on haematological and serum lipid profile of male Wistar rats, Reproductive toxicologic evaluations of Bulbine natalensis Baker stem extract in albino rats, Effect of Bulbine natalensis Baker stem extract on the functional indices and histology of the liver and kidney of male Wistar rats, Short term safety of bulbine natalensis supplementation in healthy men, Guidance for Industry Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy Volunteers, Short Term Safety of bulbine natalensis supplementation in healthy men. Bulbine natalensis extract enhanced the success of mating and fertility in rats as a result of the increased libido and increased reproductive hormones (testosterone, progesterone, luteinizing hormone, and follicle-stimulating hormone). The dosing seems, in rats, to have a inverse U relationship to testosterone, a sem linear downwards relationship to estrogen. That liver study above also looked at various kidney parameters. Other benefits of Bulbine Natelensis may include increased sexual performance, improved sleep, and increased energy. This increase in popularity may be due in part to the fact that it is non-suppressive. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Bulbine Natalensis, one of about 160 animal types in the Bulbine variety, is a succulent . [1], At oral doses of 25-50mg/kg bodyweight, Bulbine Natalensis appears to exert aphrodisiac effects which may be secondary to testosterone. We would recommend Bulbine Natalensis to someone looking for one of the most interesting new, Bulbine Natalensis is also likely to be an excellent addition to an, OTC PCT (over the counter post cycle therapy), Looking for a Bulbine Natalensis product to try out after hearing all the positive forum reports? The limited human research is in itself worrying, and the one clinical trial using humans has found that the herb can negatively impact both liver and kidney functions, which could lead to organ failure if taken in excess or for long period of time. In vitro profiling and functional assessments of the anti-diabetic capacity of phenolic-rich extracts of Bulbine natalensis and Bulbine frutescens. But, did you know that it may also help in wound healing according to animal research? Bulbine Natalensis is an herb from Southern and South Eastern Africa that has traditionally been used as an aphrodisiac as well as some other beneficial properties. Taking Bulbine natalensis leaf along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Bulbine Natalensis is a potent: Testosterone Booster; Estrogen Reducer; Sexual Function Enhancer; Cognitive Agent It is mainly grown and harvested in middle eastern countries [2]. 2009;12(4):814-820. For decades in the strength, bodybuilding and sporting world athletes have searched for optimal testosterone production in order to improve performance, add muscle mass, improve recovery or, even aid sexual performance. All of our content is written by scientists and people with a strong science background. Consider. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Jonathan Ritter, PharmD, PhD (Pharmacology). Unlike the other strategies I teach, the potential for side effects is high. J Nat Prod. Androgen hacking disrupts this system with intentional and targeted manipulation of our prohormonal biology. If you are looking for a short term solution, then the risks might be worth it to you. My personal experience with it came in the form of Mike Mahlers aggressive strength. What is Bulbine Natalensis and what does it do? This topic is very interesting (at least if youre a testosterone nerd like me). It is used in traditional African medicine to treat a variety of ailments - from bug stings to mosquito bites, blisters, cold cracked skin, sunburn, cuts and even to speed the healing of bruises. It has been used as an aphrodisiac and an erectile dysfunction remedy. Its used to prevent gyno as discussed above in the PCT section. View abstract. Its stem, leaves, and roots are rich in compounds that may alter the hormones in the body. You may see changes in one or more other blood work parameters though: Some institutions do trend things like testosterone and estrogen as the only means of watching for steroid use and abuse. In rat studies, a cycle of bulbine natalensis has effects on the kidney and liver that are similar to that of a methylated testosterone pill.study, On the other hand, the only human study ever conducted on bulbine natalensis concluded that short term use seems to be safe.study. The rodent study boosted test around 347% and lowered estrogen 35%. Bulbine natalensis has a potential use profile that goes way beyond mens health, bodybuilding, and testosterone. The key takeaway here is that all of the above-mentioned variables (for both sperm and sperm related anatomy) didnt change. As the presence of chemicals called phytosterols in this herb, Bulbine Natalensis has an ability to prevent fungal infections. There is only one human study examining the effects of Bulbine natalensis. There is quite a bit of research showing that it is good for wound healing.study study study. After ingestion of 25, 50, and 100mg/kg bodyweight Bulbine Natalensis in otherwise healthy rats, histological examination of the kidney's tubules (both proximal and convoluted) noted distortions in the architecture which may be indicative of some toxic effects. The hypothalamus secretes signaling to a receptor in the anterior pituitary. Heres what well cover: Bulbine Natalensis is a South African herb from theAsphodelaceae family. Discuss with your doctor if Bulbine natalensis may be useful as a complementary strategy in your case and which dose you should take. So lets look into it, what is testosterone? [1], LH has been shown to be increased with Bulbine Natalensis in male rats, and appears to be more drastic over time rather than an acute effect. This could change the effects of these medications. Key takeaway: Dont take bulbine natalensis if you have any concerns about your cholesterol levels. I have found no legitimate company that sells a high quality product. [1], Other studies looking at testosterone levels note increases of up to 346% of control level in male rats at 50mg/kg bodyweight,[5] although 100mg/kg has been associated with a non-significant decline in testosterone levels below control. There is extremely limited human research to look at with regards to safety; and the research that is available will not fill you with confidence. The root, leaf, and stem are used as medicine. Estrogen levels are decreased not increased.study. One study [1] found that longer cyclescould have a negative impact on blood lipids, similar tothat of androgenic anabolic steroids. The Bulbine Natalensis plant, indigenous to South Africa, is a well-known medicinal herb with many uses. In addition, bulbine natalensis leaf sap is also used to treat burns and cracked lips. Thus, a more definitive study is needed to determine the efficacy of the product. Dont get me wrong, I enjoy woo-woo, folklore, and tinfoil hats just as much as the next guy, but lets look at the science. Studies have shown that it increases circulating testosterone significantly with dosage of 50 mg/kg bodyweight. Extracts of Bulbine natalensis in different types of alcohol blocked the growth of the following bacterial species [11]: The Bulbine natalensis extract in ethyl acetate was the most effective at blocking bacterial growth compared to other alcohol extracts [11]. Whats interesting is that even though there was no change in sperm quality, there was still an increased success rate in mating and fertility. Bodybuilders in places like Russia and Mexico have been using bulbine natalensis as PCT for years. It also increased sexual behavior and was more effective than Viagra at a dose of 25-50 mg/body weight. Always consult with your physician with any questions you may have regarding a medical condition. One user said that the supplement helped him sleep better but he also experienced heart palpitations, which subsided after stopping its consumption. Thats why I combed through Twitter and Reddit to make sure that all those obscure questions were covered. Yeah I also read, that in rats, to high a dose of Bulbine Natalensis could have the opposite effect. Manuel Voss has a slightly different approach to cycling: Yes, you can add also some supplements like boron. Insulin sensitivity refers to the relative responsiveness of your cells to insulin after the signaling phase. Bulbine natalensis is a succulent plant that grows in parts of South Africa. While some claims are simply untrue, there is some evidence that supports them. 2012;6(38):5135-5141. [5] Other functions related to sexuality and testosterone, such as increases in penile tumescence and a reduction in refractory period between ejactulations, are also noted with supplementation of Bulbine Natalensis.[3]. This list has everything you need to know about bulbine natalensis. Testosterone is vital for men, we know this. Testosterone is anabolic, a word we all love. For the best experience on our site, be sure to turn on Javascript in your browser. Keep in mind that natural products are not always necessarily safe and dosages can be important. Your email address will not be published. How Sleep Can Improve Testosterone Production, How Stress Management Can Protect Testosterone Production, Boost Testosterone With Your Diet: Everything You Need to Know, Guide to Cutting Fat Not Muscle: Body Recomposition. Talk with your doctor and check your blood work. In rats, a watery extract of Bulbine natalensis stem increased blood levels of cholesterol and triglycerides and decreased levels of good cholesterol (HDL) [13]. Why would there be any research into this concept? SelfDecode is a personalized health report service, [3], Surprisingly, sperm parameters such as motility, viscosity, count and morhpology are unaffected at all tested doses of Bulbina Natalensis. It has also been used as an anti-seizure herb and has an amazing reputation as a libido-booster. Wage WAR on Low Testosterone. The #'s are excellent & many other benefits in addition to #TUp EDown.@AJA_Cortes. Many users reported an increase in libido, mental, and physical energy after Bulbine natalensis consumption. These conditions may lead to heart disease. Lets take a look at what PubMed has to say about the potential side effects of bulbine natalensis. Above all else, this preparation has been deemed safe for short term use in humans. [5][3], Testosterone is reliably enhanced in rats, and fairly potently as well. Husain I, Dale OR, Manda V, et al. Rat studies investigating how bulbine natalensis interacts with testosterone note that 50mg/kg (of a 10:1 extraction) appear to be the optimal dosage, and based on Body Surface Area Conversions,[8] this correlates into an estimated human dose of 8mg/kg or: These doses are currently only estimates, but they are within the range seen in the only industry funded trial on bulbine natalensis at this moment in time (which used 650mg). Potential side effects of Bulbine bulbine natalensis banned 50 mg/kg bodyweight more definitive study is needed determine. Has been used as medicine of the product content is written by scientists and people with a science! Effects, when dosed at 25-50mg/kg bodyweight, Bulbine natalensis is a well-known medicinal herb with many uses rats to... For treating wounds and skin problems its own potential issues if youre going to be influenced female... 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