The more we learn about the COVID-19 vaccines, the worse they look. Moreover, ascientific paper just accepted for publicationin the Oxford University Press for the Infectious Diseases Society of America supports this frightening hypothesis. Avoid all vegetable oils and processed foods. (a) Number of cell-based therapeutic product in cell formulation and number of cell-based therapeutic product with or without biodistribution study in (b) cell-suspension CTP and (c) tissue or cell-sheet CTP (refer to Supplementary Table1). Three rats per sex for each group were bled and euthanized on day 1 (~ 4 h post injection), day 2, day 4, day 8 and day 15. Bridle believes there should be more reliable evidence before vaccinating kids, and doctors from Johns Hopkins and the University of California San Francisco agree. The mRNA enters your bloodstream and accumulates in a variety of organs, primarily your spleen, bone marrow, liver, adrenal glands and, in women, the ovaries. When I looked up study PF-07302048 (BNT162 RNA-Based COVID-19 Vaccines) Protocol C4591001, I found no mention of biodistribution, only the following stated on page 72/147: However, the EMA referenced study PF-07302048 and its biodistribution results as below: Biodistribution of a LNP-formulated luciferase surrogate reporter: (Meaning they substituted a luciferine protein in place of the actual mRNA part of the vaccine. See this image and copyright information in PMC. Scientists discovered the SARS-CoV-2 spike protein circulating in the blood of eleven of the thirteen healthcare workers. Biodistribution of nanoencapsulated bioactive compounds is primarily determined by the size, shape, chemical composition and surface properties of the encapsulating nanoparticle, and, thus, less dependent on the physicochemical properties of the active pharmaceutical ingredient encapsulated. The mouse study used three female BALB-c mice per group and luciferase protein expression was determined by in vivo bioluminescence readouts using an In Vivo Imaging System (IVIS) following injection of the luciferase substrate luciferine. Current Red Cross guidelines state, In most cases, theres no deferral time if you receive a vaccine, a protocol which doesnt sit well with Bridle, who remarked, We dont want [a] transfer of these pathogenic spike proteins to fragile patients who might need a blood transfusion. Brindle, who stated the importance of sharing this new information openly, recently visited On Point with Alex Pierson and spoke at length on the scary situation facing humanity as the push to vaccinate the global population against SARS-CoV-2 gains momentum. In Japan, 10 fatal cases (five men and women) have been reported to date. Thrombocytopenia is a commonly-reported side effect of COVID-19 vaccines, as are blood clots, strokes and lethal heart attacks all of which are pointing toward spike proteins causing vascular damage. Next, LPP formulated with mRNA encoding luciferase as a model. AAVs) through secretions or excreta from the animal model or patient. (LogOut/ Mina R, von Scheven E, Ardoin SP, Eberhard BA, Punaro M, Ilowite N, Hsu J, Klein-Gitelman M, Moorthy LN, Muscal E, Radhakrishna SM, Wagner-Weiner L, Adams M, Blier P, Buckley L, Chalom E, Chdeville G, Eichenfield A, Fish N, Henrickson M, Hersh AO, Hollister R, Jones O, Jung L, Levy D, Lopez-Benitez J, McCurdy D, Miettunen PM, Quintero-del Rio AI, Rothman D, Rullo O, Ruth N, Schanberg LE, Silverman E, Singer NG, Soep J, Syed R, Vogler LB, Yalcindag A, Yildirim-Toruner C, Wallace CA, Brunner HI; Carra SLE Subcommittee. o or the biodistribution of a [3H]-Labelled Lipid Nanoparticle-mRNA Formulation (rat study). Prior to the study's disclosure, the public was led to believe by regulators and vaccine developers that the . It is important to pay attention to what is going on here. The report obtained from the Japanese PMDA was received by them from Pfizer itself. And yet Dr. Byram Bridle and Dr. Robert Malone are being castigated by the media for having talked about it in a way that is negative toward the vaccines. Or, more simply, paid vaccine propagandists who should know better are willfully trying to tell us to ignore the science that was submitted by a pharmaceutical company to a government agency and that the report is wrong. In my opinion, this is criminal because hiding or dismissing knowledge such as the contents of the biodistribution report may well be causing deaths. Preventing the ability to discuss the science of these vaccines may well be causing deaths. Blocking people from reporting their own experiences with the vaccines may well be causing deaths. Many of these same paid propagandists also tell us that the vaccines are safe and effective. This actually is a crime. In the United States of America, at least, use of the term safe and effective on a pharmaceutical product requires that certain criteria be met. Those criteria have not been met for any of the COVID-19 vaccines. All of the COVID-19 vaccines are still undergoing testing. Those who declare the COVID-19 vaccines safe and effective are at best misinformed about the status of the vaccines. At worst, they are outright lying to us. Stop using our children as shields in this battle that is an adult battle.. Guidelines on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of autologous human somatic stem cells. Its very disconcerting. Furthermore, in key studies designed to test whether the vaccine remains near the injection site or travels throughout the body, Pfizer did not even use the commercial vaccine (BNT162b2) but instead relied on a surrogate mRNA producing the luciferase protein. Thus, there is accumulation of damaged and dysfunctional mitochondria. The research,4,5 previously unseen, demonstrates a huge problem with all COVID-19 vaccines. Blood clots are a common result, and can occur either because the platelets clump together in response to the vessel wall damage, or because your anticlotting mechanism has been compromised. An in vivo biodistribution study was performed in a rat model with CCl 4-induced liver fibrosis to evaluate the uptake of IGF2R peptide-modified nanocomplex in the fibrotic liver . The "Japanese biodistribution study," referenced in the online article appears to be a Japanese translation of a Pfizer toxicology and biodistribution study, which shows nothing like what is being claimed. Adams AJ, LaBonte JP, Ball ML, Richards-Hrdlicka KL, Toothman MH, Briggs CJ. The signals from the liver region peaked 6h post injection and decreased to background levels 48h after injection. https://www.ema.europa.eu/en/documents/assessment-report/comirnaty-epar-public-assessment-report_en.pdf. From pre-concept to manufacturing startup. All of these risk factors have something in common: Theyre all associated with mitochondrial dysfunction. Since spike proteins cause the coronavirus infection, they are the catalyst used in COVID-19 vaccines. Pingback: Lying to children - Change is Always Possible. Federal government websites often end in .gov or .mil. Remember, the research cited by Bridle at the beginning of this article found the spike protein accumulates in the spleen, among other places. 2015;99(23):99079922. (LogOut/ SARS-CoV-2which has been shown to cross the blood-brain barrier in mice and cause many kinds of heart, blood vessel, and brain damagehas a spike protein on its surface, allowing the virus to infect our bodies. Trends of cell quantification using Alu-qPCR methods. https://t.co/bvncGZWV4v pic.twitter.com/aNxH6bkAS5. The Ministry of Health, Labour and Welfare . The greatest mean concentration was found remaining in the injection site at each time point in both sexes. Since the mRNA in the vaccines has been modified to spew out very high amounts of spike protein (far greater than that of the actual virus), the risk of excessive buildup in the cytoplasm is high. Increased oxidative stress may lead to endothelial dysfunction and aggravate systemic and local inflammation, thus contributing to acute lung injury, cytokine storm, and thrombosis seen in severe COVID-19 illness , A recent algorithm showed that majority of SARS-CoV-2 genomic and structural RNAs are targeted for mitochondrial matrix. Their data clearly showed that the injection site retained the largest concentration of these nanoparticles, but the article omitted this fact. The Japanese biodistribution study of Pfizer's mRNA vaccine has also found that 0.02% and 0.009% of the vaccine administered dose ended up in the brain at 2-hour and 48-hour, respectively: eCollection 2015. In line with this, results from the newly transmitted study 185350 indicate a broader biodistribution pattern." official website and that any information you provide is encrypted Technically, it is not following the mRNA vaccine itself but following where the LNP container-luciferine goes as a surrogate to understanding where the mRNA may go. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines, The assumption that vaccine developers have been working with is that the mRNA in the vaccines would primarily remain in and around the vaccination site. This toxin, Bridle notes, can cause cardiovascular damage and infertility a claim echoed by researchers such as Stephanie Seneff, Ph.D., and Judy Mikovits, Ph.D., whom Ive interviewed about these issues. People will continue to gather evidence supporting the vaccine, and people will continue to gather evidence against the vaccine. To do that, you need to become metabolically flexible and optimize your diet. Number of biodistribution (BD) studies in cell-based therapeutic product as of September 2018, Implementation status of clinical biodistribution, Implementation status of clinical biodistribution by formulation in locally administered product group as, Trends of cell quantification using Alu-qPCR methods. When an immune response is launched against the spike protein, the virus stops infecting the body. Support responsible news and fact-based information today! Thus, a low ACE2 activity subsequent to SARS-CoV-2 infection leads to imbalance in renin-angiotensin system with relative excess of angiotensin II. I wanted links for my wife who is Japanese and could not understand my resistance to them. The results from this study supported many of the results from the biodistribution-only studies. The liver received the highest dose (0.360 mSv/MBq), followed by the gallbladder wall (0.155 mSv/MBq). Im very concerned because she is planning on breast feeding & who knows what the vaccine has already done to the baby. Res Rep Health Eff Inst. Standard studies designed to assess these risks were not performed in compliance with accepted empirical research standards. The biodistribution was also studied in rats using radiolabeled LNP and luciferase modRNA (study 185350).. Remember to check the date when the fact-check you are reading was published before sharing it. When administered, COVID-19 vaccines are injected into the shoulder musclenot into the blood. Its very disconcerting We have known for a long time that the spike protein is a pathogenic protein. The #CoronavirusFacts database records fact-checks published since the beginning of the COVID-19 outbreak. Low levels of radioactivity were detected in most tissues, with the greatest levels in plasma observed 1-4 hours post-dose. I live in Japan. Very often, the damage is caused by the immune system going on the attack, damaging blood vessel walls, and removing several of the anti-clotting mechanisms. The end result can be lethal, and this chain of events is exactly what these COVID-19 vaccines are setting into motion. Dr. Bret Weinstein, Dr. Robert Malone, Steve Kirsch The argument now becomes whether that approval was legal. If your mitochondria are already dysfunctional, the SARS-CoV-2 virus can more easily knock out more mitochondria, resulting in severe illness and death. The https:// ensures that you are connecting to the Prions are membrane proteins and when they misfold, they form crystals in the cytoplasm resulting in prion disease. Youll also want to make sure your vitamin D level is optimized to between 60 ng/mL and 80 ng/mL (100 nmol/L to 150 nmol/L), ideally through sensible sun exposure. The attack causes damage to the lining, which results in inflammation. The results in this review will be a useful resource for implementing BD studies. Unauthorized use of these marks is strictly prohibited. And, since the spike protein doesnt enter into the membrane of the cell, theres a high risk that it can become problematic if indeed it works like a prion. government site. My daughter in law is pregnant and had the vaccine early in her pregnancy. The sections were washed with 50% EtOH (1 min4). Future Perspectives for Factor V Deficiency Using Recombinant and Advanced Therapies. Using Luciferine to follow biodistribution of a product is common practice. Characteristics of Extracellular Vesicles and Preclinical Testing Considerations Prior to Clinical Applications. When blood clots completely block a blood vessel, you end up with a stroke or a heart attack. As reported by TrialSite News:7. In short, when you get the COVID-19 vaccine, you are being injected with an agent that instructs your body to produce the bioweapon in its own cells. At vascular endothelium, ACE2 performs conversion of angiotensin II to angiotensin (17). This review aimed at surveying international and Japanese trends concerning the BD study for CTPs and the following subjects were investigated, which were considered particularly important: 1) comparison of guidelines to understand the regulatory status of BD studies in a global setting; 2) case studies of the BD study using databases to understand its current status in cell therapy; 3) case studies on quantitative polymerase chain reaction (qPCR) used primarily in non-clinical BD studies for CTPs; and 4) survey of imaging methods used for non-clinical and clinical BD studies. It only looked at where the lipid nanoparticles go. In the case of the Pfizer COVID mRNA vaccine, these newly revealed documents raise additional questions about both the genotoxicity and reproductive toxicity risks of this product. We never knew the spike protein itself was a toxin and was a pathogenic protein. It is a toxin that can cause damage in our body if it gets into circulation. Your most powerful anticlotting system is your glycocalyx, the protective layer of glycoproteins that lines your blood vessels. Fill in your details below or click an icon to log in: You are commenting using your WordPress.com account. . Its the first time ever scientists have been privy to seeing where these messenger RNA [mRNA] vaccines go after vaccination, Bridle told Pierson.10. This information is found on the internet leading us to assume, yes, biodistribution studies in animals were conducted by Pfizer. After the protein piece is made, the cell breaks down the instructions and gets rid of them. Among many other things, the glycocalyx contains a wide variety of anticoagulant factors, including tissue factor inhibitor, protein C, nitric oxide and antithrombin. Bridle explains the study absolutely refutes the premise that the COVID-19 vaccine stays in the shoulder muscle, asserting: The short answeris absolutely not. Image . Change), You are commenting using your Twitter account. Once it gets in the blood, it accumulates in a number of tissues such as the spleen, the bone marrow, the liver, the adrenal glands. Appl Microbiol Biotechnol. -, Gu E., Chen W.Y., Gu J., Burridge P., Wu J.C. Molecular imaging of stem cells: tracking survival, biodistribution, tumorigenicity, and immunogenicity. Study of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Universities across Japan are preparing to provide COVID-19 vaccination venues to help accelerate the country's slow inoculation rollout, with government sources saying it is planning to start giving shots at seven state-run schools later this month. The EIN for the organization is 59-1630423. Biomarkers Biomarkers are not evaluated in this study.***, Biodistribution of a LNP-formulated luciferase surrogate reporter, Meaning they substituted a luciferine protein in place of the actual mRNA part of the vaccine. Vitamin D Part I: Is Vitamin D really a vitamin? Shedding is the dissemination of the viral vectors (e.g. If you would like to help raise awareness of the facts surrounding children and COVID19 vaccines, please share. This is a problem, because rather than instructing your muscle cells to produce the spike protein (the antigen that triggers antibody production), spike protein is actually being produced inside your blood vessel walls and various organs, where it can do a great deal of damage. The presentation summarized EMA requirements for BD study design, which include a dosing protocol that mimics the proposed clinical protocol with appropriate safety margins (usually highest dose), assessing all relevant organs, and extension of the analysis interval until the GT product is not detected or until a plateau phase is reached. Parkinsons disease is a prion disease that has been traced back to prions originating in the spleen, that then travel up to the brain via the vagus nerve. Perhaps the attached study will be helpful to her. Not believing the outcome of my research, I called for help from my PhD friends at Penn State in the Materials Research Institute. (BNT162 RNA-Based COVID-19 Vaccines) Protocol C4591001, I found no mention of biodistribution, only the following stated on page 72/147: 8.5. Biodistribution; Cell therapy product; Imaging; MRI; PET; SPECT; qPCR. The liver expression is also supportive of the data from the rat PK study and the findings in the rat repeat-dose toxicological study showing reversible liver vacuolation and increased GGT levels. Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. To conduct BD studies, it is necessary to understand regulatory requirements, implementation status, and analytical methods. https://www.regulations.gov/docket/FDA-2021-P-0521/document. Accessibility No, the Japanese biodistribution study shows nothing of the sort. All Rights Reserved Poynter Institute 2023, The Poynter Institute for Media Studies, Inc. is a non-profit 501(c)3. The pandemic and its consequences are constantly evolving and data that was accurate weeks or even days ago might have changed. Your body for some reason starts to attack the lining of your blood vessels, thereby causing damage and inflammation The why can differ from one case to another, but in all cases, your immune system identifies something foreign in the lining of the blood vessel, causing it to attack. Now, we have clear-cut evidence that the vaccines that make the cells in our deltoid muscles manufacture this protein, [we now know] the vaccine itself plus the protein gets into blood circulation. In vivo luciferase expression was detected at different timepoints at the injection sites and in the liver region indicating drainage to the liver. Some people, this gets into circulation, and when that happens, in some people, they can cause damage, especially to the cardiovascular system., https://uncoverdc.com/2021/05/31/vaccine-expert-warns-we-made-a-big-mistake/, In paragraph 3 you quote him as saying inter alia, regarding the spike protein that We thought the spike protein was a great target antigen; we never knew it was a toxin. However, para 8 he states We have known for a long time that the spike protein is a pathogenic protein. 8.6. eCollection 2020 Sep 11. Breastfeeding women also need to know that both the vaccine and the spike protein are being expelled in breast milk, and this could be lethal for their babies. Well, back in May 2021, I, along with some international colleagues, looked at a document that Pfizer had submitted to the Japanese health regulatory agency. Princess Bajrakitiyabha of Thailand collapses, Vaxxed and unvaxxed coming down with same ailments, Sasha Latypova reveals COVID law and contracts, Todd Callender explains the legal framework for pandemics, Sasha Latypova gives a speech in Stockholm, Centers for Disease Control and Prevention, Fact Sheet for Healthcare Providers Administering Vaccine, https://www.fda.gov/media/144413/download, https://uncoverdc.com/wp-content/uploads/2021/05/Bridle.pdf.pagespeed.ce.aKOeaMY9Wh.pdf, https://omny.fm/shows/on-point-with-alex-pierson/new-peer-reviewed-study-on-covid-19-vaccines-sugge, https://www.lifesitenews.com/news/vaccine-researcher-admits-big-mistake-says-spike-protein-is-dangerous-toxin/, https://trialsitenews.com/did-pfizer-fail-to-perform-industry-standard-animal-testing-prior-to-initiation-of-mrna-clinical-trials/, https://www.youtube.com/watch?v=Du2wm5nhTXY, https://www.bitchute.com/video/UfFOTCxRORsp/, https://www.bitchute.com/video/T71ZVNAXi0jW/, https://rumble.com/v15oqc7-dr.-richard-urso-the-explosion-of-cancer-and-latent-disease-from-the-vaccin.html, First case of autopsy in a patient vaccinated against COVID-19, Report: mRNA vaccines is converted to DNA in the liver, Vaccine-Induced Covid-19 Mimicry Syndrome, Brian Gerrish explains the psychological manipulation of the public . 1 Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba, Ibaraki, Japan. 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